Cic edizioni internazionali
Muscle, Ligaments and Tendons Journal

Evidence of healing of partial-thickness rotator cuff tears following arthroscopic augmentation with a collagen implant: a 2-year MRI follow-up

Original Article, 16 - 25
doi: 10.11138/mltj/2016.6.1.016
Tag this article
Abstract
Enhanced HTML Full text PDF
Background: partial-thickness rotator cuff tears frequently enlarge due to increased local strain and often progress to full-thickness tears. Studies suggest the addition of new tendinous tissue to injured cuff tendons would significantly decrease peak strain, possibly protecting against tear progression.
The aim of this study was to assess the ability of a highly-porous collagen implant to induce new tissue formation and limit tear progression when placed on the bursal surface of partialthickness cuff tears.
Methods: following arthroscopic subacromial decompression, the implant was attached to the bursal surface of the supraspinatus tendon in a prospective series of 13 consecutive patients with intermediate – (3-6 mm) to high-grade (>6 mm) partial – thickness cuff tears (5 articular, 3 bursal, 5 intra-substance). Tendon thickness, defect size, and tendon quality were evaluated using magnetic resonance imaging (MRI) preoperatively and at 3, 6, 12, and 24 months postoperatively. Clinical outcomes were assessed using the Constant and American Shoulder and Elbow Society scores at the same preoperative and follow-up times. All 13 patients completed all follow-up exams (mean length of follow-up 27.0 months, range 23.3-32.0); no patients were lost to follow-up.
Results: the implant induced significant new tissue formation in all patients by 3 months (mean increase in tendon thickness 2.2 ± 0.26 mm). This tissue matured over time and became radiologically indistinguishable from the underlying tendon.
The partial-thickness cuff tears showed consistent filling of the defects, with complete healing in 7 patients at 12 months, and a progressive improvement in tendon quality in the remaining patients. No tear progression was observed by
MRI in any of the patients at 24 months. All clinical scores improved significantly over time. At 24 months, 12 of 13 patients (92%) had satisfactory or better results.
Conclusions: the results of this clinical study demonstrated the ability of a highly-porous collagen implant to induce new tendon-like tissue formation and create an environment conductive to the healing of partial-thickness cuff tears.

Vol. 7 (No. 2) 2017 April/June

  1. Knocking-out matrix metalloproteinase-13 exacerbates rotator cuff muscle fatty infiltration
    Liu X., Ravishankar B., Ning A., Liu M., Kim H.T., Feeley B.T.
  2. Hyaluronic acid increases tendon derived cell viability and proliferation in vitro: comparative study of two different hyaluronic acid preparations by molecular weight
    Gallorini M., Berardi A.C., Berardocco M., Gissi C., Maffulli N., Cataldi A., Oliva F.
  3. Lactoferrin and parathyroid hormone are not harmful to primary tenocytes in vitro, but PDGF may be
    Musson D.S., Tay M.L., Chhana A., Pool B., Coleman B, Naot D., Cornish J.
  4. Cox-2 inhibition and the composition of inflammatory cell populations during early and mid-time tendon healing
    Blomgran P., Blomgran R., Ernerudh J., Aspenberg P.
  5. How to evaluate bone tunnel widening after ACL reconstruction - a critical review
    de Beus A., Koch J. EJ, Hirschmann A., Hirschmann M.T.
  6. Minimally invasive anatomic reconstruction of the anterolateral ligament with ipsilateral gracilis tendon
    Trinchese G.F., Oliva F., Maffulli N.
  7. Arthroscopic ACL reconstruction using patellar bone tendon autograft and Rigidfix fixation - A midterm functional outcome
    Sudevan P.J., Chandrasekharan J., Sambandam S.N., Rohinikumar G.J., Annamalai S., Mounasamy V.
  8. Effects of tendon-bone healing of anterior cruciate ligament reconstruction by osteoprotegerin combined with deproteinized bovine bone
    Zou G., Song E., Wei B.
  9. Reverse shoulder arthroplasty patient personalized rehabilitation protocol. Preliminary results according to prognostic groups
    Romano A.M., Oliva F., Nastrucci G., Casillo P., Di Giunta A., Susanna M., Ascione F.
  10. Reverse total shoulder versus angular stable plate treatment for proximal humeral fractures in over 65 years old patients
    Giardella A., Ascione F., Mocchi M., Berlusconi M., Romano A.M., Oliva F., Maradei L.
  11. Normal microscopic architecture of acetabular labrum of hip joint: a qualitative original study with clinical aspects
    Kapetanakis S., Gkantsinikoudis N., Dermon A., Kommata V., Papathanasiou J., Soukakos P., Dermon C.
  12. Effects of hip flexion angle on surface electromyographic activity of the biceps femoris and semitendinosus during isokinetic knee flexion
    Kellis E., Galanis N., Kofotolis N., Hatzi A.
  13. Functional leg length discrepancy between theories and reliable instrumental assessment: a study about newly invented NPoS system
    Mahmoud A., Abundo P., Basile L., Albensi C., Marasco M., Bellizzi L., Galasso F., Foti C.
  14. Characterising the proximal patellar tendon attachment and its relationship to skeletal maturity in adolescent ballet dancers
    Rudavsky A., Cook J., Magnusson S.P., Kjaer M., Docking S.
  15. The Royal London Hospital Test for the clinical diagnosis of patellar tendinopathy
    Maffulli N., Oliva F., Loppini M., Aicale R., Spiezia F., King J.B.
  16. Reliability of a device for the knee and ankle isometric and isokinetic strength testing in older adults
    Bergamin M., Gobbo S., Bullo V., Vendramin B., Duregon F., Frizziero A., Di Blasio A., Cugusi L., Zaccaria M., Ermolao A.
  17. Ultrasound guided injection of a painful knee osteoarthritis with medial meniscus extrusion: a case series study
    Di Sante L., Venditto T., Ioppolo F., Paoloni M., Mangone M., Alviti F.
  18. Percutaneous release of the plantar fascia. New surgical procedure
    Oliva F., Piccirilli E., Tarantino U., Maffulli N.
  19. Endoscopic Flexor Halluces Longus transfer for Chronic Achilles Tendon rupture - technique description and early post-operative results
    Baumfeld D., Baumfeld T., Figueiredo A.R., de Araujo Junior L.F., Macedo B., Alves Silva T.A., Raduan F., Nery C.
  20. Triceps surae elasticity modulus measured by shear wave elastography is not correlated to the plantar flexion torque
    Lima K., Martins N., Pereira W., Oliveira L.
  21. Soft tissue pseudotumours: a pictorial review with emphasis on MRI
    Perdikakis E., Tsifountoudis I., Kalaitzoglou I., Rountas C., Malliaropoulos N., Maffulli N.
  22. Perivascular Adductor Longus muscle injury: Ultrasound and Magnetic Resonance Imaging findings
    Mattiussi G., Baldassi P.T., Pasta G., Burani A., Moreno C.
  23. Efficacy and safety of hyaluronic acid (500-730kDa) Ultrasound-guided injections on painful tendinopathies: a prospective, open label, clinical study
    Fogli M., Giordan N., Mazzoni G.
  24. Failed synthetic graft after acute Achilles tendon repair
    Mohmed A., Oliva F., Nardoni S., Maffulli N.
Last Viewed articles: la lista degli ultimi x visitati.
  1. Evidence of healing of partial-thickness rotator cuff tears following arthroscopic augmentation with a collagen implant: a 2-year MRI follow-up
    Bokor D.J., Sonnabend D., Deady L., Cass B., Young A., Van Kampen C., Arnoczky S.
    doi: 10.11138/mltj/2016.6.1.016
credits